Prophylactic vaccinations are saving lives
The discovery and development of prophylactic or preventive vaccines remains one of the major successes of global health saving millions of lives every year. (PMID: 34197271)
Today, more than 20 life-threatening diseases can be prevented by prophylactic vaccination, helping people of all ages live longer and healthier lives.
Furthermore, the widespread use of COVID-19 mRNA vaccines accelerates mRNA vaccine technology leading to the development of future prophylactic as well as cancer vaccines.
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Pandemics and Health Emergencies
Future pandemics are inevitable, but it is unlikely, that vaccine production plants can be scaled up rapidly enough to immunize the critical proportion of 60–70% of the world’s population. Therefore, dose-sparing approaches such as intradermal vaccination can offer a solution.
Dose-sparing effect of a fractional prophylactic vaccination dose
Numerous studies show that for vaccines like Hepatitis B, influenza, rabies, Polio, Yellow Fever and SARS-CoV-2 and others, intradermal (ID) prophylactic vaccination using a fractional dose of 1/5th or even 1/10th of the full dose exhibits a similar or non-inferior immune response compared to intramuscular (IM) or subcutaneous (SC) vaccination. (PMID: 32898704; White paper on prophylactic vaccination)
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VAX-ID for reliable intradermal vaccination
The study by Van Mulder et al. published in the peer-reviewed journal Vaccine, showed that vaccination with a fractional dose, i.e. 1/5th of the full dose, recombinant hepatitis B vaccine administered by VAX-ID showed similar immune responses as full dose IM.
Importantly, VAX-ID is CE marked and be used with vaccines authorized for intradermal use.
Curious to find out more about VAX-ID? Check out the VAX-ID product page here.
Intradermal prophylactic vaccination applications
Getting to the heart of our applications and learn more about the science behind the intradermal route of administration for vaccines against: